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Chemistry Of Natural Products

Chemistry Of Natural Products
Author: Sujata V. Bhat
Publisher: Springer Science & Business Media
ISBN: 9783540406693
Size: 74.96 MB
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During the last few decades, research into natural products has advanced tremendously thanks to contributions from the fields of chemistry, life sciences, food science and material sciences. Comparisons of natural products from microorganisms, lower eukaryotes, animals, higher plants and marine organisms are now well documented. This book provides an easy-to-read overview of natural products. It includes twelve chapters covering most of the aspects of natural products chemistry. Each chapter covers general introduction, nomenclature, occurrence, isolation, detection, structure elucidation both by degradation and spectroscopic techniques, biosynthesis, synthesis, biological activity and commercial applications, if any, of the compounds mentioned in each topic. Therefore it will be useful for students, other researchers and industry. The introduction to each chapter is brief and attempts only to supply general knowledge in the particular field. Furthermore, at the end of each chapter there is a list of recommended books for additional study and a list of relevant questions for practice.
Chemistry of Natural Products
Language: en
Pages: 840
Authors: Sujata V. Bhat, B.A. Nagasampagi, Meenakshi Sivakumar
Categories: Science
Type: BOOK - Published: 2005-01-04 - Publisher: Springer Science & Business Media
During the last few decades, research into natural products has advanced tremendously thanks to contributions from the fields of chemistry, life sciences, food science and material sciences. Comparisons of natural products from microorganisms, lower eukaryotes, animals, higher plants and marine organisms are now well documented. This book provides an easy-to-read overview of natural products. It includes twelve chapters covering most of the aspects of natural products chemistry. Each chapter covers general introduction, nomenclature, occurrence, isolation, detection, structure elucidation both by degradation and spectroscopic techniques, biosynthesis, synthesis, biological activity and commercial applications, if any, of the compounds mentioned in each topic. Therefore it will be useful for students, other researchers and industry. The introduction to each chapter is brief and attempts only to supply general knowledge in the particular field. Furthermore, at the end of each chapter there is a list of recommended books for additional study and a list of relevant questions for practice.
The Chemistry of Natural Products
Language: en
Pages: 453
Authors: R.H. Thomson
Categories: Science
Type: BOOK - Published: 1993-09-30 - Publisher: Springer Science & Business Media
This book reviews in a concise and manageable way the progress in all key areas of natural products chemistry since 1984. The most significant advances are highlighted over a wide field of chemistry, structure, synthesis and biosynthesis. This book provides a unique and superb entry into the vast literature on the subject.
Studies in Natural Products Chemistry
Language: en
Pages: 458
Authors: Atta-ur-Rahman
Categories: Science
Type: BOOK - Published: 2020-07-03 - Publisher: Elsevier
Studies in Natural Products Chemistry: Bioactive Natural Products, Volume 65, the latest in a series that covers the synthesis or testing and recording of the medicinal properties of natural products, provides cutting-edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products. Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to quickly isolate and determine the structures and biological activity of natural products. This has opened up exciting opportunities in the field of new drug development to the pharmaceutical industry. Focuses on the chemistry of bioactive natural products Contains contributions by leading authorities in the field Presents sources of new pharmacophores
Progress in the Chemistry of Organic Natural Products 114
Language: en
Pages: 337
Authors: A. Douglas Kinghorn, Heinz Falk, Simon Gibbons, Jun'ichi Kobayashi, Yoshinori Asakawa, Ji-Kai Liu
Categories: Science
Type: BOOK - Published: 2021-04-19 - Publisher: Springer
This book describes current understandings and recent progress in four areas: in the first one, the cytochalasans, a group of fungal derived natural products characterized by a perhydro-isoindolone core fused with a macrocyclic ring are shown to exhibit high structural diversity and a broad spectrum of bioactivities. The second one is dedicated to a description of bioactive compounds from the medicinal plants of Myanmar, the third one is dedicated to new structure elucidation techniques in the field of sesquiterpenes. The last one discusses the endogenous natural products that are produced by human cells including endogenous amines, steroids, and fatty acid derived natural products. The co-metabolism and natural product production of the human microbiome is also described including tryptophan, bile acids, choline, and cysteine.
Studies in Natural Products Chemistry
Language: en
Pages: 438
Authors: Atta-ur- Rahman
Categories: Science
Type: BOOK - Published: 2012-12-06 - Publisher: Elsevier
Natural products play an integral and ongoing role in promoting numerous aspects of scientific advancement, and many aspects of basic research programs are intimately related to natural products. With articles written by leading authorities in their respective fields of research, Studies in Natural Products Chemistry, Volume 37 presents current frontiers and future guidelines for research based on important discoveries made in the field of bioactive natural products. It is a valuable source for researchers and engineers working in natural products and medicinal chemistry. Describes the chemistry of bioactive natural products Contains contributions by leading authorities in the field A valuable source for researchers and engineers working in natural product and medicinal chemistry
Fortschritte der Chemie Organischer Naturstoffe/Progress in the Chemistry of Organic Natural Products
Language: de
Pages: 456
Authors: L. Zechmeister
Categories: Science
Type: BOOK - Published: 2012-01-11 - Publisher: Springer
BARTON und COHEN haben r9S7 in einer Arbeit "Some Biogenetic Aspects of Phenol Oxidation" (3) Dienone der allgemeinen Formel (I) als biogenetische Vorstufen bestimmter Aporphin-Alkaloide postuliert (S. 260). Strukturen dieses Typs wurden erstmals r963 fUr die Alkaloide D-( +)-Pronuciferin und D-( +)-Crotonosin bewiesen [BERNAUER (II); HAYNES, STUART, BARTON und KIRBY (35)]. Der fur solche Verbin­ dungen vorgeschlagene Sammelname "Proaporphine" (23, 65) bringt den in zwischen experimentell bewiesenen· biogenetischen Zusammenhang mit der Gruppe der Aporphin-Alkaloide zum Ausdruck, ist aber auch vom praparativ-chemischen Standpunkt sinnvoll, da sich Proaporphine (I) leicht in Aporphine (2) umwandeln lassen (S. 2S0). AuBer den Alkaloiden mit Dienongruppierung sind auch solche be­ kannt geworden, in welchen eine oder mehrere Doppelbindungen des Dienonsystems aushydriert sind; sie werden sinnvollerweise den Pro­ aporphinen zugerechnet. Dieser Aufsatz berucksichtigt alle natiirlichen Alkaloide und ihre wichtigsten Derivate sowie alle synthetischen Ver­ bindungen, die das Skelett (3) besitzen (Tabellen I-3, SS. 270-279). Er macht ausschlieBlich von der in (3) angegebenen Bezifferung Gebrauch, welche der Nomenklatur der IUPAC und der Chemical Abstracts ent­ spricht. Verbindung (I, R = H) ist wie folgt zu bezeichnen: 2',3',8',8'a-Tetra­ hydro-S',6'-dihydroxy-spiro[2,S-cyclohexadien-r,7'(r'H)-cyclopent[ij]-iso­ chinolin ]-4-on. R2 (2) K=H oder Alkyl (I) R=H oder Alkyl Rt=H,OH oder O-Alkyl Proaporphine Aporphine In den Originalarbeiten sind
Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products
Language: en
Pages: 376
Authors: L. Zechmeister
Categories: Science
Type: BOOK - Published: 2012-02-12 - Publisher: Springer
The chemistry of condensed tannins has hitherto represented a relatively unattractive and therefore neglected area of study; one in which the weight of research effort involved is invariably disproportionate to the results achieved, in which the participating schools generally confine their approach to specific molecular species, and in which as yet no consensus has been reached regarding likely precursors. The problems which beset those engaged in this field represent a combined function of the abnormal complexity of the gradational range of oligomers of increasing mass and affinity for substrates which typify most extracts rich in tannins, and the consequent problem of their isolation and purification, the high chirality of tannin oligomers, the need to contend with the phenomenon of dynamic 'rotational isomerism about interflavanoid bonds in the IH n.m.r. spectral interpretation of their derivatives, the lack of precise knowledge regarding the points of bonding at nucleophilic centres, and the obvious limitations of a hitherto predominantly analytical approach. The last of these reflects the need for a general method of synthesis which permits unambiguous proof of both structure and absolute configuration also at higher oligomeric levels. With these objectives in mind we initiated a purely synthetic approach based on the premise
Chemistry for Pharmacy Students
Language: en
Pages: 536
Authors: Lutfun Nahar, Professor Satyajit D. Sarker
Categories: Science
Type: BOOK - Published: 2019-08-26 - Publisher: John Wiley & Sons
Introduces the key areas of chemistry required for all pharmacy degree courses and focuses on the properties and actions of drug molecules This new edition provides a clear and comprehensive overview of the various areas of general, organic, and natural products chemistry (in relation to drug molecules). Structured to enhance student understanding, it places great emphasis on the applications of key theoretical aspects of chemistry required by all pharmacy and pharmaceutical science students. This second edition particularly caters for the chemistry requirements in any ‘Integrated Pharmacy Curricula’, where science in general is meant to be taught ‘not in isolation’, but together with, and as a part of, other practice and clinical elements of the course. Chemistry for Pharmacy Students: General, Organic and Natural Product Chemistry, 2nd Edition is divided into eight chapters. It opens with an overview of the general aspects of chemistry and their importance to modern life, with emphasis on medicinal applications. The text then moves on to discuss the concepts of atomic structure and bonding and the fundamentals of stereochemistry and their significance to pharmacy in relation to drug action and toxicity. Various aspects of organic functional groups, organic reactions, heterocyclic chemistry, nucleic acids and their pharmaceutical
The Chemistry of Natural Products Related to Phenanthrene
Language: en
Pages: 358
Authors: Louis Frederick Fieser
Categories: Phenanthrene
Type: BOOK - Published: 1936 - Publisher:
The chemistry of phenanthrene and some instances of the occurrence of phenanthrene and hydrophenanthrene derivatives. Resin acids. Cancer-producing hydrocarbons. Sterols and bile acids. Sex hormones. Heart poisons. Saponins.
Studies in Natural Products Chemistry
Language: en
Pages: 470
Authors: Louis Frederick Fieser
Categories: Science
Type: BOOK - Published: 2016-07-05 - Publisher: Elsevier
Studies in Natural Products Chemistry, Volume 48, provides the latest on the use of natural products from the plant and animal kingdom and the ways in which they can offer a huge diversity of chemical structures, which are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then rapidly determine the structures and biological activity of natural products, thus opening up exciting opportunities in the field of new drug development. The series covers all aspects of the science, along with the synthesis, testing, and recording of the medicinal properties of natural products. With articles written by leading authorities in their respective fields of research, the book presents current frontiers and future guidelines for research based on important discoveries made in the field of bioactive natural products. It is a valuable resource for all those working in natural product and medicinal chemistry. Provides the latest on the use of natural products from the plant and animal kingdom and the ways in which they can offer a huge diversity of chemical structures Focuses on the